Different tires on each side

Have 3 slightly used Falken Wildpeak At3Ws and 1 brand new wildpeak at4w. Is the ~7 pound weight difference going to pose problems in the long run for my axle? I have a Dana 44 in the rear and a Dana 30 in the front (03 Jeep Grand Cherokee), I will probably put the brand new tire on the left rear.